This framework recognizes the critical role of public health leaders and partners in carrying out a comprehensive, cross-sector response to the opioid crisis. With effective leadership and cross-sector partnerships, states and territories can leverage four key strategies in their work, including (1) training and education; (2) monitoring and surveillance; (3) treatment, recovery and harm reduction; and (4) primary and overdose prevention. Each element of the framework was assessed for the level of evidence supporting the recommendation.

Monitoring and Surveillance

Training and Education

Primary and Overdose Protection

Treatment, Recovery and Harm Reduction


State Approaches for Promoting Family-Centered Care for Pregnant and Postpartum Women with Substance Use Disorders

ASTHO released an ASTHOBrief describing family-centered care programs for pregnant and postpartum women with substance use disorder.

Regional Differences in the Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2017

A report from the National Vital Statistics System outlined regional differences in the specific drugs most often involved in overdose deaths.

Map of Neonatal Abstinence Syndrome Among Newborn Hospitalizations

The Healthcare Utilization Project created this interactive map examining the rate of neonatal abstinence syndrome-related newborn hospitalizations by state. The map also displays data related to patient characteristics, expected payer, cost, and length of stay.

Leadership from key leaders in governmental and nongovernmental agencies across multiple levels (federal, state, and local) and sectors (health, public safety, corrections, drug control, and education) is needed to comprehensively address the opioid epidemic within states and territories. Partnerships promote the cross-cutting, multisector collaboration needed to develop and sustain appropriate strategies and tactics for accomplishing state and local goals and objectives around addressing the opioid epidemic. Resources are critical for the successful implementation of these strategies and tactics.