This framework recognizes the critical role of public health leaders and partners in carrying out a comprehensive, cross-sector response to the opioid crisis. With effective leadership and cross-sector partnerships, states and territories can leverage four key strategies in their work, including (1) training and education; (2) monitoring and surveillance; (3) treatment, recovery and harm reduction; and (4) primary and overdose prevention. Each element of the framework was assessed for the level of evidence supporting the recommendation.

Monitoring and Surveillance

Training and Education

Primary and Overdose Protection

Treatment, Recovery and Harm Reduction


Feds to Let States Tap Opioid Funds for Meth, Cocaine Surge

Federal funding earmarked for the opioid epidemic can now be used to address methamphetamine and cocaine use.

Using Medicaid to Advance Evidence-Based Treatment of Substance Use Disorders: A Toolkit for State Medicaid Leaders

This Manatt Health report discusses promising strategies, action steps, and implementation tools for state Medicaid directors to consider adopting to address the opioid crisis.

Leaders Seek to Elevate Racial Disparities to Top-of-Mind Issue

Addiction treatment professionals continue to elevate the issue of racial disparities in access to high-quality substance use treatment. 

Leadership from key leaders in governmental and nongovernmental agencies across multiple levels (federal, state, and local) and sectors (health, public safety, corrections, drug control, and education) is needed to comprehensively address the opioid epidemic within states and territories. Partnerships promote the cross-cutting, multisector collaboration needed to develop and sustain appropriate strategies and tactics for accomplishing state and local goals and objectives around addressing the opioid epidemic. Resources are critical for the successful implementation of these strategies and tactics.